Publications

Link to Google Scholar Page

Link to Pubmed Publications Page

2024

Flexible, scalable, high channel count stereo electrode for recording in the human brain

Lee K, Paulk AC, et al., Nature Communications 

DOI: 10.1088/1741-2552/ad2404

PMID: 38233418

Neural activity of retinal ganglion cells under continuous dynamically-modulated high frequency electrical stimulation

Muralidharan M, Guo T, Tsai D, Fried SI, Dokos S, Morley JW, Lovell NH, Shivdasani MN Journal of Neural Engineering

DOI: 10.1088/1741-2552/ad2404

PMID: 38290151

2023

MEMS micro-coils for magnetic neurostimulation

Liu X, Whalen AJ, et al., Biosensors and Bioelectronics

DOI: 10.1016/j.bios.2023.115143

PMID: 36805270

Layer-dependent stability of intracortical recordings and neuronal cell loss

Urdaneta ME, Kunigk NG, et al., Frontiers Neuroscience

DOI:10.3389/fnins.2023.1096097

PMID: 37090803

Thermal safety considerations for implantable micro-coil design

Whalen AJ & Fried SI, J. Neural Engineering

DOI: 10.1088/1741-2552/ace79a

PMID: 37451256

Neuromodulation and Neural Technologies for Sight Restoration (Editorial)

Im M, Zeck GM, et al., Frontiers Neuroscience

DOI:10.3389/fncel.2023.1304872.

PMID: 37915374

2022

Magnetic stimulation allows focal activation of the mouse cochlea

Lee JI, Seist R, et al., eLife​

DOI: 10.7554/eLife.76682

PMID: 35608242

Micro-magnetic stimulation of primary visual cortex induces focal and sustained activation of secondary visual cortex

Lee SW & Fried SI, Phil. Transactions Royal Society A

DOI: 10.1098/rsta.2021.0019

PMID: 35658677

The long-term stability of intracortical microstimulation and the foreign body response are layer dependent

Urdaneta ME, Kunigk NG, et al., Frontiers Neuroscience

DOI: 10.3389/fnins.2022.908858

PMID: 35769707

Thermal Effects on Neurons During Stimulation of the Brain

Kim T, Kadji H, et al., J. Neural Engineering

DOI: 10.1088/1741-2552/ac9339

PMID: 36126646

2021

Microscale physiological events on the human cortical surface detected with PEDOT:PSS Electrodes

Paulk AC, Yang JC, et al., Cerebral Cortex

DOI: 10.1093/cercor/bhab040

PMID: 33749727

The impact of synchronous versus asynchronous electrical stimulation in artificial vision

Moleirinho S, Whalen AJ, et al., J. Neural Engineering

DOI: 10.1088/1741-2552/abecf1

PMID: 33900206

Layer-Specific Parameters of Intracortical Microstimulation of the Somatosensory Cortex

Urdaneta ME, Kunigk NG, et al., J. Neural Engineering

DOI:10.1088/1741-2552/abedde

PMID: 33706301

MEMS inductor fabrication and emerging applications in power electronics and neurotechnologies

Le H, Haque R, et al., Nature Microsystems and Nanoengineering

DOI: 10.1038/s41378-021-00275-w

PMID: 34567771

Spiking Characteristics of Network-Mediated Responses Arising in Direction-Selective Ganglion Cells of Rabbit and Mouse Retinas

Otgondemberel Y, Roh H, et al., IEEE-Transactions Neural Systems & Rehabilitation Eng.

DOI:10.1109/TNSRE.2021.3128878

PMID: 34784280

Morphological factors that underlie neural sensitivity to simulation in the retina

Raghuram V, Werginz P, et al., Advanced NanoBiomed Research

DOI:10.1002/anbr.202100069

PMID: 35399546 

2020

The eye and the chip 2019 – Conference report

Rathbun D, Shivdasani M, et al., J. Neural Engineering

DOI:10.1088/1741-2552/ab60c0

PMID: 31965978

News and Views: Selective activation of the visual cortex

Fried SI & Shivdasani MN, Nature Biomedical Engineering

DOI: 10.1038/s41551-020-0419-8 

PMID: 32051575.

Noninvasive electrical stimulation improves photoreceptor survival and retinal function in mice with inherited photoreceptor degeneration

Yu H, Enayati S, et al., IOVS

DOI:10.1167/iovs.61.4.5

PMID: 32271885

Neural activity of functionally different retinal ganglion cells can be robustly modulated by high-rate electrical pulse trains

Muralidharan M, Guo T, et al., J. Neural Engineering

DOI: 10.1088/1741-2552

PMID: 32512555

Towards controlling functionally-distinct retinal ganglion cells in degenerate retina

Muralidharan M, Guo T, et al., Conf Proc Engineering in Medicine & Biological Science

DOI:10.1109/EMBC44109.2020.9176595

PMID: 33018781

Differential responses to high-frequency stimulation in brisk transient and delta ganglion cells

Hadjinicolaou A, Werginz P, et al., Conf Proc Engineering in Medicine & Biological Science

DOI:10.1109/EMBC44109.2020.9175276

PMID: 33018765

Response profiles of retinal ganglion cells to sinusoidal electric stimulation vary for low and high frequencies

Lee JI, Hadjinicolaou AE, et al., Conf Proc Engineering in Medicine & Biological Science

DOI:10.1109/EMBC44109.2020.9175373 

PMID: 33018766

Retinal Degeneration Reduces Consistency of Network-mediated Responses Arising in Ganglion Cells to Electric Stimulation

Yoon YJ, Lee JI, et al., IEEE-Transactions Neural Systems & Rehabilitation Engineering

DOI:10.1109/TNSRE.2020.3003345

PMID: 32746297

The relationship between morphological properties and extracellular electric stimulation in alpha RGCs

Werginz P, Raghuram V, et al., J. Neural Engineering

DOI: 10.1088/1741-2552/abab47

PMID: 32736374

Tailoring of the axon initial segment underlies reliable conversion of synaptic inputs into spiking output in OFF-Alpha T retinal ganglion cells

Werginz P, Raghuram V, et al., Science Advances

DOI:10.1126/sciadv.abb6642

PMID: 32917708

Spatially confined responses of mouse visual cortex to intracortical magnetic stimulation from micro-coils

Ryu SB, Paulk AC, et al., J. Neural Engineering

DOI:10.1088/1741-2552/abbd22

PMID: 32998116

2019

Micro-coil design influences the spatial extent of responses to intracortical magnetic stimulation

Lee SW, Thyagarajan K, et al., IEEE Transactions BioMedical Engineering

DOI: 10.1109/TBME.2018.2877713 

PMID: 30369434

Response of visual cortical neurons in the mouse to electric stimulation of the retina

Ryu SB, Werginz P, et al., Frontiers in Neuroscience

DOI:10.3389/fnins.2019.00324

PMID: 31019449.

Mediating Retinal Ganglion Cell Spike Rates Using High-Frequency Electrical Stimulation

Guo T, Tsai D, et al., Frontiers Neuroscience

DOI: 10.3389/fnins.2019.00413

PMID: 31114476

Comparison of electrically elicited responses in rabbit and mouse retinal ganglion cells.

Werginz P & Fried SI, Conf Proc Engineering in Medicine & Biological Science

DOI: 10.1109/EMBC.2019.8857504

PMID:31946249

Selective Formation of Porous Pt Nanorods for Highly Electrochemically Efficient Neural Electrode Interfaces

Ganji M, Paulk A, et al., Nano Letters Article

DOI: 10.1021/acs.nanolett.9b02296

PMID: 31369283

Somatodendritic and AIS scaling in retinal ganglion cells helps to regulate spike properties and maintain response consistency

Raghuram V, Werginz P, et al., Frontiers Cellular Neuroscience

DOI: 10.3389/fncel.2019.00436.

PMID: 31611777

2018

Electric stimulus duration alters network-mediated responses depending on retinal ganglion cell type

Im M, Werginz P, et al., J. Neural Engineering

DOI:10.1088/1741-2552/aaadc1

PMID: 29415876

Visual and electric spiking signatures of seven types of rabbit retinal ganglion cells

Werginz P, Im M, et al., Conf Proc Engineering in Medicine & Biological Science

DOI:10.1109/EMBC.2018.8512746

PMID: 30440899

Micro-solenoid inductors with magnetic core for neural stimulation

Zaeimbashi M, Wang Z, et al., Conf Proc Engineering in Medicine & Biological Science

DOI: 10.1109/EMBC.2018.8512729

 PMID: 30440849

Comparison of responses of visual cortical neurons in the mouse to intraocular and extraocular stimulation of the retina

Ryu SB & Fried S, Conf Proc IEEE Eng Med Biol Sci.

DOI: 10.1109/EMBC.2018.8512795 

PMID: 30440905

2017

Network-mediated Responses of ON Ganglion Cells to Electric Stimulation Become Less Consistent across Trials during Retinal Degeneration

Lee, JI, Fried SI, et al., Conf Proc Engineering in Medicine & Biological Science.

DOI:10.1109/EMBC.2017.8037271 

PMID: 29060314

A Sub-millimeter, Inductively Powered Neural Stimulator

Freeman DK, O'Brien JM, et al., Frontiers in Neuroscience

DOI: 10.3389/fnins.2017.00659

PMID: 29230164

2016

Temporal properties of network-mediated responses to repetitive stimuli are dependent upon retinal ganglion cell type

Im M & Fried SI, J. Neural Engineering

DOI:10.1088/1741-2560/13/2/025002 

PMID: 26905231

Directionally selective ganglion cells suppress luminance responses during natural viewing

Im M & Fried SI, Nature Scientific Reports

DOI:10.1038/srep35708

PMID: 27759086

Implantable micro-coils for intracortical magnetic stimulation

Lee SW, Fallegger F, et al., Science Advances

DOI:10.1126/sciadv.1600889 

PMID: 27957537

Enhanced control of cortical pyramidal neurons with micro-magnetic stimulation

Lee SW & Fried SI, IEEE-Transactions Neural Systems & Rehabilitation Engineering

DOI:10.1109/TNSRE.2016.2631446 

PMID: 27893396

2015

The retinal response to sinusoidal electric stimulation

Twyford P & Fried SI, IEEE-Transactions Neural Systems & Rehabilitation Engineering

DOI:10.1109/TNSRE.2015.2415811

PMID: 25850091

Indirect activation elicits strong correlations between light and electrical responses in ON but not OFF retinal ganglion cells

Im M & Fried SI, J. Physiology

DOI: 10.1113/JP270606

PMID: 26033477

2014

Differential response to high-frequency electric stimulation

Twyford P, Cai C, et al., J. Neural Engineering

DOI:10.1088/1741-2560/11/2/025001

PMID: 24556536

Influence of the sodium channel on retinal ganglion cell excitation during electric stimulation - A modeling study

Werginz P, Fried SI, et al., Neuroscience

DOI:10.1016/j.neuroscience.2014.01.067  

PMID: 24560986

Suppression of subthalamic nucleus activity by micro-magnetic stimulation

Lee SW & Fried SI, IEEE-Transactions Neural Systems & Rehabilitation Engineering

DOI: 10.1109/TNSRE.2014.2348415

PMID: 25163063

The response of L5 pyramidal neurons of the PFC to magnetic stimulation from a micro-coil

Lee SW & Fried SI, Conf Proc Engineering in Medicine & Biological Science

DOI:10.1109/EMBC.2014.6945027

PMID: 25571395

Selective activation of ON and OFF retinal ganglion cells to high frequency electric stimulation: a computational modeling study

Guo T, Lovell NH, et al., Conf Proc IEEE Engineering in Medicine & Biological Science

DOI:10.1109/EMBC.2014.6945023

PMID: 25571391

2013

Ephrin-A3 Suppresses Wnt Signaling to Control Retinal Stem Cell Potency

Fang Y, Cho KS, et al., Stem Cells

DOI:10.1002/stem.1283

PMID: 23165658

Responses to pulsatile subretinal electric stimulation: effects of amplitude and duration

Lee SW, Eddington DK, et al., J. Neurophysiology

DOI:10.1152/jn.00293.2012

PMID: 23343891

The response of retinal neurons to high-frequency stimulation

Cai C, Twyford P, et al., J. Neural Engineering

DOI:10.1088/1741-2560/10/3/036009

PMID: 23594620

2012

Microscopic magnetic stimulation of neural tissue

Bonmassar G, Lee SW, et al., Nature Communications

DOI:10.1038/ncomms1914 

PMID: 22735449

2011

Multiple components of ganglion cell desensitization in response to prosthetic stimulation

Freeman DK & Fried SI, J. Neural Engineering

DOI:10.1088/1741-2560/8/1/016008

PMID: 21248379

The sodium channel band shapes the response to electric stimulation in retinal ganglion cells

Jeng J, Tang S, et al., J. Neural Engineering

DOI:10.1088/1741-2560/8/3/036022

PMID: 21558602

Calcium channel dynamics limit synaptic release in response to prosthetic stimulation with sinusoidal waveforms a computational study

Freeman DK, Jeng JS, et al., J. Neural Engineering

DOI:10.1088/1741-2560/8/4/046005

PMID: 21628768

Response variability to high rates of electric stimulation in retinal ganglion cells

Cai, C, Ren, Q, et al., J. Neurophysiology

DOI:10.1152/jn.00956.2010

PMID: 21490287

Encoding Visual Information in Retinal Ganglion Cells with Prosthetic Stimulation

Freeman, DK, Rizzo, JF, Fried, SI. (2011), J. Neural Engineering

DOI:10.1088/1741-2560/8/3/035005

PMID: 21593546

High frequency electric stimulation of retinal neurons elicits physiological signaling patterns

Fried SI, Cai C, et al., Conf Proc IEEE Engineering in Medicine and Biology

DOI: 10.1109/IEMBS.2011.6090251

PMID: 22254500

2010

Electric stimulation with sinusoids and white noise for neural prostheses

Freeman DK, Rizzo JF, et al., Frontiers Neuroprosthetics

DOI:10.3389/neuro.20.001-4

PMID: 20582268

Selective Activation of Neuronal Targets with Sinusoidal Electric Stimulation

Freeman DK, Eddington DK, et al., J. Neurophysiology

DOI:10.1152/jn.00551.2010

PMID: 20810683

2009

Axonal sodium channel bands shape the response to electric stimulation in retinal ganglion cells

Fried SI, Lasker AC, et al., J. Neurophysiology

DOI:10.1152/jn.91081.2008

PMID: 19193771

2007

Image processing: How the retina detects the direction of image motion

Fried SI & Masland RH, Current Biology

DOI:10.1016/j.cub.2006.12.013

PMID: 17240332

2006

A method for generating precise temporal patterns of retinal spiking using prosthetic devices 

Fried SI, Hsueh HA, et al., J. Neurophysiology

DOI:10.1152/jn.00849.2005

PMID: 16236780

2005

Directional selectivity is formed at multiple levels by laterally offset inhibition in the rabbit retina

Fried SI, Münch TA, et al., Neuron

DOI:10.1016/j.neuron.2005.02.007 

PMID: 15820698

2002

Mechanisms and circuitry underlying directional selectivity in the retina.

Fried SI, Münch TA, et al., Nature

DOI:10.1038/nature01179 

PMID: 12459782

1987

Carbon dioxide laser use in wound sealing and epikeratophakia

Keates RH, Fried SI, et al., Journal of Cataract & Refractive Surgery

DOI: 10.1016/s0886-3350(87)80073-1 

PMID: 3108490

1986

Analysis of cat multi-channel acoustic brain-stem response data using dipole localization methods 

Gaumond RP & Fried SI, Electroencephalography and Clinical Neurophysiology

DOI:10.1016/0013-4694(86)90023-4

PMID: 2419096

Books and book chapters

2017

Precise and reliable activation of cortex with micro-coils

Brain-Computer Interface Research: A State-of-the-Art Summary 6, C.Guger, Ed., Springer Nature

Lee, SW and Fried SI, (2017).

DOI: 10.1007/978-3-319-64373-1_3

2011

Electric stimulation of the retina: the contribution of animal studies

Fried SI and Jensen, RJ

Retinal Prosthetics, G.Dagnelie, Ed., Springer.

DOI: 10.1007/978-1-4419-0754-7_12

2007

Generating precise patterns of retinal spiking

Fried SI, Hsueh HA & Werblin FS

Proceedings of the 2nd Annual Dept. of Energy (DOE) Conference on Retinal Prosthetics, Ft. Lauderdale, Florida (USA).

Contact

Dr. Shelley Fried
– Associate Professor of Neurosurgery
– Director, Neural Prosthetic Research Laboratory

Address: 50 Blossom Street, Boston, Massachusetts, 02114

Email: fried.shelley@ mgh.harvard.edu

Department of Neurosurgery
Massachusetts General Hospital
Harvard Medical School

News

Home Institutions